loading...| Preferred Name | Didanosine [Chemical/Ingredient] | |
| Synonyms |
Dideoxyinosine Inosine, 2',3'-dideoxy- Didanosine ddI (Antiviral) 2',3'-Dideoxyinosine |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006111 |
|
| altLabel |
Dideoxyinosine Inosine, 2',3'-dideoxy- Didanosine ddI (Antiviral) 2',3'-Dideoxyinosine |
|
| cui |
C0012133 |
|
| Ingredient of | ||
| MESH DEFINITION |
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite. |
|
| MESH DUI |
D016049 |
|
| MeSH name |
Didanosine |
|
| MESH UI |
M0024535 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000006111 |
|
| NUI |
N0000006111 |
|
| prefLabel |
Didanosine [Chemical/Ingredient] |
|
| tui |
T114 T121 |
|
| subClassOf |