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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Dideoxynucleosides [Chemical/Ingredient] | |
Synonyms |
ddNus Dideoxynucleosides |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000008043 |
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altLabel |
ddNus Dideoxynucleosides
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cui |
C0012136
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MESH DEFINITION |
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
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MESH DUI |
D015224
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MeSH name |
Dideoxynucleosides
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MESH UI |
M0023387
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000008043
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NUI |
N0000008043
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prefLabel |
Dideoxynucleosides [Chemical/Ingredient]
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tui |
T114
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subClassOf |
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