loading...| Preferred Name |
Polyendocrinopathies, Autoimmune [Disease/Finding] |
|
| Synonyms |
Polyendocrinopathies, Autoimmune |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000003500 |
|
| altLabel |
Polyendocrinopathies, Autoimmune |
|
| cui |
C0085409 |
|
| MESH DEFINITION |
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present. |
|
| MESH DUI |
D016884 |
|
| MeSH name |
Polyendocrinopathies, Autoimmune |
|
| MESH UI |
M0025689 |
|
| NDFRT kind |
DISEASE_KIND |
|
| notation |
N0000003500 |
|
| NUI |
N0000003500 |
|
| prefLabel |
Polyendocrinopathies, Autoimmune [Disease/Finding] |
|
| SNOMED CID |
41864002 |
|
| tui |
T047 |
|
| subClassOf |