National Drug File - Reference Terminology - Epilepsy, Tonic-Clonic [Disease/Finding] - Classes

National Drug File - Reference Terminology

Last uploaded: July 6, 2018

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Preferred Name	Epilepsy, Tonic-Clonic [Disease/Finding]
Synonyms	Tonic-Clonic Seizure Syndrome Epilepsy, Grand Mal Major Motor Seizure Disorder Tonic-Clonic Convulsion Disorder Convulsions, Grand Mal Tonic-Clonic Seizure Disorder Tonic Clonic Convulsions Seizure Disorder, Grand Mal Tonic-Clonic Convulsion Syndrome Epilepsy, Tonic-Clonic Seizure Disorder, Major Motor Seizure Disorder, Tonic Clonic Epilepsy, Major Grand Mal Seizure Disorder
ID	http://purl.bioontology.org/ontology/NDFRT/N0000001129
altLabel	Tonic-Clonic Seizure Syndrome Epilepsy, Grand Mal Major Motor Seizure Disorder Tonic-Clonic Convulsion Disorder Convulsions, Grand Mal Tonic-Clonic Seizure Disorder Tonic Clonic Convulsions Seizure Disorder, Grand Mal Tonic-Clonic Convulsion Syndrome Epilepsy, Tonic-Clonic Seizure Disorder, Major Motor Seizure Disorder, Tonic Clonic Epilepsy, Major Grand Mal Seizure Disorder
cui	C0014549
May be treated by	http://purl.bioontology.org/ontology/NDFRT/N0000148644 http://purl.bioontology.org/ontology/NDFRT/N0000163160 http://purl.bioontology.org/ontology/NDFRT/N0000164059 http://purl.bioontology.org/ontology/NDFRT/N0000165112 http://purl.bioontology.org/ontology/NDFRT/N0000161793 http://purl.bioontology.org/ontology/NDFRT/N0000164660 http://purl.bioontology.org/ontology/NDFRT/N0000153025 http://purl.bioontology.org/ontology/NDFRT/N0000192495 http://purl.bioontology.org/ontology/NDFRT/N0000150659 http://purl.bioontology.org/ontology/NDFRT/N0000148988 http://purl.bioontology.org/ontology/NDFRT/N0000193647 http://purl.bioontology.org/ontology/NDFRT/N0000023138 http://purl.bioontology.org/ontology/NDFRT/N0000160900 http://purl.bioontology.org/ontology/NDFRT/N0000162315 http://purl.bioontology.org/ontology/NDFRT/N0000190457 http://purl.bioontology.org/ontology/NDFRT/N0000150750 http://purl.bioontology.org/ontology/NDFRT/N0000191388 http://purl.bioontology.org/ontology/NDFRT/N0000180989 http://purl.bioontology.org/ontology/NDFRT/N0000148974 http://purl.bioontology.org/ontology/NDFRT/N0000178197 http://purl.bioontology.org/ontology/NDFRT/N0000178253 http://purl.bioontology.org/ontology/NDFRT/N0000148991 http://purl.bioontology.org/ontology/NDFRT/N0000023137 http://purl.bioontology.org/ontology/NDFRT/N0000177410 http://purl.bioontology.org/ontology/NDFRT/N0000146226 http://purl.bioontology.org/ontology/NDFRT/N0000178254 http://purl.bioontology.org/ontology/NDFRT/N0000178194 http://purl.bioontology.org/ontology/NDFRT/N0000164060 http://purl.bioontology.org/ontology/NDFRT/N0000147040 http://purl.bioontology.org/ontology/NDFRT/N0000150753 http://purl.bioontology.org/ontology/NDFRT/N0000182606 http://purl.bioontology.org/ontology/NDFRT/N0000177411 http://purl.bioontology.org/ontology/NDFRT/N0000148972 http://purl.bioontology.org/ontology/NDFRT/N0000150667 http://purl.bioontology.org/ontology/NDFRT/N0000150752 http://purl.bioontology.org/ontology/NDFRT/N0000163184 http://purl.bioontology.org/ontology/NDFRT/N0000146807 http://purl.bioontology.org/ontology/NDFRT/N0000148493 http://purl.bioontology.org/ontology/NDFRT/N0000178195 http://purl.bioontology.org/ontology/NDFRT/N0000184114 http://purl.bioontology.org/ontology/NDFRT/N0000146576 http://purl.bioontology.org/ontology/NDFRT/N0000178212 http://purl.bioontology.org/ontology/NDFRT/N0000150749 http://purl.bioontology.org/ontology/NDFRT/N0000163158 http://purl.bioontology.org/ontology/NDFRT/N0000150658 http://purl.bioontology.org/ontology/NDFRT/N0000153026 http://purl.bioontology.org/ontology/NDFRT/N0000192496 http://purl.bioontology.org/ontology/NDFRT/N0000182604 http://purl.bioontology.org/ontology/NDFRT/N0000192494 http://purl.bioontology.org/ontology/NDFRT/N0000150751 http://purl.bioontology.org/ontology/NDFRT/N0000147059 http://purl.bioontology.org/ontology/NDFRT/N0000190095 http://purl.bioontology.org/ontology/NDFRT/N0000162605 http://purl.bioontology.org/ontology/NDFRT/N0000154304 http://purl.bioontology.org/ontology/NDFRT/N0000148976 http://purl.bioontology.org/ontology/NDFRT/N0000150748 http://purl.bioontology.org/ontology/NDFRT/N0000161786 http://purl.bioontology.org/ontology/NDFRT/N0000190971 http://purl.bioontology.org/ontology/NDFRT/N0000190804 http://purl.bioontology.org/ontology/NDFRT/N0000148989 http://purl.bioontology.org/ontology/NDFRT/N0000150663 http://purl.bioontology.org/ontology/NDFRT/N0000178198 http://purl.bioontology.org/ontology/NDFRT/N0000160899 http://purl.bioontology.org/ontology/NDFRT/N0000181642 http://purl.bioontology.org/ontology/NDFRT/N0000162314 http://purl.bioontology.org/ontology/NDFRT/N0000148979 http://purl.bioontology.org/ontology/NDFRT/N0000180916 http://purl.bioontology.org/ontology/NDFRT/N0000182605 http://purl.bioontology.org/ontology/NDFRT/N0000177931 http://purl.bioontology.org/ontology/NDFRT/N0000192662 http://purl.bioontology.org/ontology/NDFRT/N0000190806 http://purl.bioontology.org/ontology/NDFRT/N0000146212 http://purl.bioontology.org/ontology/NDFRT/N0000162606 http://purl.bioontology.org/ontology/NDFRT/N0000178256 http://purl.bioontology.org/ontology/NDFRT/N0000145811 http://purl.bioontology.org/ontology/NDFRT/N0000190096 http://purl.bioontology.org/ontology/NDFRT/N0000162842 http://purl.bioontology.org/ontology/NDFRT/N0000178257 http://purl.bioontology.org/ontology/NDFRT/N0000190805 http://purl.bioontology.org/ontology/NDFRT/N0000150661 http://purl.bioontology.org/ontology/NDFRT/N0000190802 http://purl.bioontology.org/ontology/NDFRT/N0000178196 http://purl.bioontology.org/ontology/NDFRT/N0000161694 http://purl.bioontology.org/ontology/NDFRT/N0000148978 http://purl.bioontology.org/ontology/NDFRT/N0000148973 http://purl.bioontology.org/ontology/NDFRT/N0000178535 http://purl.bioontology.org/ontology/NDFRT/N0000190094 http://purl.bioontology.org/ontology/NDFRT/N0000178199 http://purl.bioontology.org/ontology/NDFRT/N0000163156 http://purl.bioontology.org/ontology/NDFRT/N0000023139 http://purl.bioontology.org/ontology/NDFRT/N0000145810 http://purl.bioontology.org/ontology/NDFRT/N0000190803 http://purl.bioontology.org/ontology/NDFRT/N0000178255 http://purl.bioontology.org/ontology/NDFRT/N0000163784 http://purl.bioontology.org/ontology/NDFRT/N0000146211 http://purl.bioontology.org/ontology/NDFRT/N0000162313 http://purl.bioontology.org/ontology/NDFRT/N0000150660 http://purl.bioontology.org/ontology/NDFRT/N0000192085 http://purl.bioontology.org/ontology/NDFRT/N0000190093 http://purl.bioontology.org/ontology/NDFRT/N0000191389 http://purl.bioontology.org/ontology/NDFRT/N0000190458 http://purl.bioontology.org/ontology/NDFRT/N0000161794 http://purl.bioontology.org/ontology/NDFRT/N0000160898 http://purl.bioontology.org/ontology/NDFRT/N0000192497 http://purl.bioontology.org/ontology/NDFRT/N0000189940
MESH DEFINITION	A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
MESH DUI	D004830
MeSH name	Epilepsy, Tonic-Clonic
MESH UI	M0007573
NDFRT kind	DISEASE_KIND
notation	N0000001129
NUI	N0000001129
prefLabel	Epilepsy, Tonic-Clonic [Disease/Finding]
SNOMED CID	352818000
tui	T047
subClassOf	http://purl.bioontology.org/ontology/NDFRT/N0000001128

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MDRFRE/10010918	MDRFRE	CUI
http://purl.bioontology.org/ontology/MEDDRA/10018659	MEDDRA	CUI
http://purl.bioontology.org/ontology/CST/CONVULS%20GRAND%20MAL	COSTART	CUI
http://purl.bioontology.org/ontology/MEDDRA/10044001	MEDDRA	CUI
http://purl.bioontology.org/ontology/MEDDRA/10025452	MEDDRA	CUI
http://purl.bioontology.org/ontology/MDRGER/10025452	MDRGER	CUI
http://purl.bioontology.org/ontology/RCD/XM03h	RCD	CUI
http://purl.bioontology.org/ontology/MEDDRA/10015041	MEDDRA	CUI
http://purl.bioontology.org/ontology/SNMI/DA-30210	SNMI	CUI
http://purl.bioontology.org/ontology/MDRFRE/10018659	MDRFRE	CUI
http://purl.bioontology.org/ontology/MEDDRA/10009343	MEDDRA	CUI
http://purl.bioontology.org/ontology/MDRFRE/10015041	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRFRE/10018660	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRFRE/10025452	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRGER/10018659	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRFRE/10043998	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRGER/10010918	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRFRE/10043999	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRGER/10010909	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRGER/10015041	MDRGER	CUI
http://purl.bioontology.org/ontology/MEDDRA/10010909	MEDDRA	CUI
http://purl.bioontology.org/ontology/RCD/F2510	RCD	CUI
http://purl.bioontology.org/ontology/MDRGER/10009343	MDRGER	CUI
http://purl.bioontology.org/ontology/MEDDRA/10018658	MEDDRA	CUI
http://purl.bioontology.org/ontology/MDRFRE/10018658	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRGER/10043999	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRFRE/10009343	MDRFRE	CUI
http://purl.bioontology.org/ontology/MEDDRA/10043999	MEDDRA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D004830	MSHFRE	CUI
http://purl.bioontology.org/ontology/MDRFRE/10010909	MDRFRE	CUI
http://purl.bioontology.org/ontology/MDRGER/10018658	MDRGER	CUI
http://purl.bioontology.org/ontology/WHOFRE/0095	WHOFRE	CUI
http://purl.bioontology.org/ontology/MEDDRA/10010918	MEDDRA	CUI
http://purl.bioontology.org/ontology/MEDDRA/10043998	MEDDRA	CUI
http://purl.bioontology.org/ontology/WHO/0095	WHO-ART	CUI
http://purl.bioontology.org/ontology/MDRGER/10044001	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRGER/10018660	MDRGER	CUI
http://purl.bioontology.org/ontology/ICPC2P/N88008	ICPC2P	CUI
http://purl.bioontology.org/ontology/MDRGER/10043998	MDRGER	CUI
http://purl.bioontology.org/ontology/MDRFRE/10044001	MDRFRE	CUI
http://purl.bioontology.org/ontology/MESH/D004830	MESH	CUI
http://purl.bioontology.org/ontology/MEDDRA/10018660	MEDDRA	CUI
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000001129	ODAE	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000001129	OCVDAE	LOOM