Preferred Name |
Metronidazole |
|
Synonyms |
Flagyl I.V. RTU METRONIDAZOLE metronidazole Metronidazole Flagyl Tricom |
|
Definitions |
A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C651 |
|
ALT_DEFINITION |
A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic. |
|
CAS_Registry |
443-48-1 |
|
CHEBI_ID |
CHEBI:6909 |
|
Chemical_Formula |
C6H9N3O3 |
|
code |
C651 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA HemOnc |
|
DEFINITION |
A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. |
|
FDA_UNII_Code |
140QMO216E |
|
FULL_SYN |
Flagyl I.V. RTU METRONIDAZOLE metronidazole Metronidazole Flagyl Tricom |
|
Has_Salt_Form | ||
label |
Metronidazole |
|
Legacy Concept Name |
Metronidazole |
|
NSC Number |
50364 69587 |
|
Preferred_Name |
Metronidazole |
|
prefixIRI |
Thesaurus:C651 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0025872 |
|
subClassOf |