Preferred Name |
Cloxacillin |
|
Synonyms |
Cloxacillin CLOXACILLIN |
|
Definitions |
A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61688 |
|
CAS_Registry |
61-72-3 |
|
CHEBI_ID |
CHEBI:49566 |
|
Chemical_Formula |
C19H18ClN3O5S |
|
code |
C61688 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
Display_Name |
Cloxacillin |
|
FDA_UNII_Code |
O6X5QGC2VB |
|
FULL_SYN |
Cloxacillin CLOXACILLIN |
|
Has_Salt_Form | ||
label |
Cloxacillin |
|
Legacy Concept Name |
Cloxacillin |
|
NCI_Drug_Dictionary_ID |
813342 |
|
Preferred_Name |
Cloxacillin |
|
prefixIRI |
Thesaurus:C61688 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0009077 |
|
subClassOf |