National Cancer Institute Thesaurus

Last uploaded: November 25, 2019
Preferred Name

Ciprofloxacin

Synonyms

Cipro

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid

ciprofloxacin

CIPROFLOXACIN

Ciprofloxacin

Definitions

A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375

Accepted_Therapeutic_Use_For

Inhaled anthrax, post-exposure; Susceptible infectious diseases

ALT_DEFINITION

A drug that is used to treat infections caused by bacteria and is being studied in the treatment of bladder cancer. Cipro is a type of fluoroquinolone.

CAS_Registry

85721-33-1

CHEBI_ID

CHEBI:100241

Chemical_Formula

C17H18FN3O3

code

C375

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. (NCI04)

FDA_UNII_Code

5E8K9I0O4U

FULL_SYN

Cipro

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid

ciprofloxacin

CIPROFLOXACIN

Ciprofloxacin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47976

label

Ciprofloxacin

Legacy_Concept_Name

Ciprofloxacin

PDQ_Closed_Trial_Search_ID

40784

PDQ_Open_Trial_Search_ID

40784

Preferred_Name

Ciprofloxacin

prefixIRI

ncit:C375

Semantic_Type

Organic Chemical

Antibiotic

UMLS_CUI

C0008809

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C280

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795

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http://purl.bioontology.org/ontology/UATC/J01MA02 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 EFO LOOM
http://purl.bioontology.org/ontology/CSP/5004-0016 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002939 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907004431328874 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147503 NDFRT LOOM
http://purl.bioontology.org/ontology/UATC/S03AA07 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372840008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55710 SNMI LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0001799 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.186 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP15380-6 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Ciprofloxacin GALEN LOOM
http://purl.obolibrary.org/obo/ARO_0000036 ARO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040784 PDQ LOOM
http://purl.bioontology.org/ontology/NDDF/002882 NDDF LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147503 ODAE LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#DMTO_0001799 FASTO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004599 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/S01AE03 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008809 OCHV LOOM
http://purl.jp/bio/4/id/200906033484858081 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D002939 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/2551 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4019307 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3001 OCHV LOOM
http://www.drugbank.ca/drugs/DB00537 FTC LOOM
http://purl.bioontology.org/ontology/UATC/S02AA15 ATC LOOM