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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Edoxaban Tosylate | |
| Synonyms |
N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-(N,N- dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro(1,3)thiazolo(5,4-c)pyridine-2- carboxamido)cyclohexyl)oxamide, 4- methylbenzenesulfonate Edoxaban Tosylate Edoxaban Tosilate EDOXABAN TOSYLATE DU-176b Savaysa |
|
| Definitions |
The tosylate salt form of edoxaban, an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96542 |
|
| CAS_Registry |
480449-71-6
|
|
| Chemical_Formula |
C24H30ClN7O4S.C7H8O3S
|
|
| code |
C96542
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 |
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| Contributing_Source |
FDA
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|
| DEFINITION |
The tosylate salt form of edoxaban, an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.
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|
| FDA_UNII_Code |
32W99UE810
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|
| FULL_SYN |
N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-(N,N- dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro(1,3)thiazolo(5,4-c)pyridine-2- carboxamido)cyclohexyl)oxamide, 4- methylbenzenesulfonate Edoxaban Tosylate Edoxaban Tosilate EDOXABAN TOSYLATE DU-176b Savaysa
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Edoxaban Tosylate
|
|
| NCI_Drug_Dictionary_ID |
758684
|
|
| PDQ_Closed_Trial_Search_ID |
758684
|
|
| PDQ_Open_Trial_Search_ID |
758684
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|
| Preferred_Name |
Edoxaban Tosylate
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|
| prefixIRI |
Thesaurus:C96542
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C3272851
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|
| subClassOf |
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