National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ulipristal

Synonyms

11-beta-(4-(dimethylamino)phenyl)-17-hydroxy-19-norpregna-4,9-diene-3,20-dione

ULIPRISTAL

Ulipristal

Definitions

A selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91056

CAS_Registry

159811-51-5

Chemical_Formula

C28H35NO3

code

C91056

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception.

FDA_UNII_Code

6J5J15Q2X8

FULL_SYN

11-beta-(4-(dimethylamino)phenyl)-17-hydroxy-19-norpregna-4,9-diene-3,20-dione

ULIPRISTAL

Ulipristal

label

Ulipristal

Preferred_Name

Ulipristal

prefixIRI

Thesaurus:C91056

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0300205

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1891

Delete Subject Author Type Created
No notes to display