loading...| Preferred Name |
Brotizolam |
|
| Synonyms |
2-Bromo-4-(O-Chlorophenyl)-9-Methyl-6H-Thieno(3,2-F)-S-Triazolo(4,3-A)(1,4)Diazepine 6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine,2-Bromo-4-(2-Chlorophenyl)-9-Methyl- BROTIZOLAM Brotizolam WE-941 |
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| Definitions |
A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87057 |
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| CAS_Registry |
57801-81-7 |
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| Chemical_Formula |
C15H10BrClN4S |
|
| code |
C87057 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine binding site on the gamma aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS. |
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| FDA_UNII_Code |
5XZM1R3DKF |
|
| FULL_SYN |
2-Bromo-4-(O-Chlorophenyl)-9-Methyl-6H-Thieno(3,2-F)-S-Triazolo(4,3-A)(1,4)Diazepine 6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine,2-Bromo-4-(2-Chlorophenyl)-9-Methyl- BROTIZOLAM Brotizolam WE-941 |
|
| label |
Brotizolam |
|
| Preferred_Name |
Brotizolam |
|
| prefixIRI |
Thesaurus:C87057 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0054151 |
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| subClassOf |