Link to this page
National Cancer Institute Thesaurus
| Preferred Name | Sodium Salicylate | |
| Synonyms |
sodium salicylate Salicylate, sodium Sodium Salicylate Benzoic acid, 2-hydroxy-, monosodium salt Sodium salicylate SODIUM SALICYLATE |
|
| Definitions |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C834 |
|
| Accepted_Therapeutic_Use_For |
Fever; Inflammatory conditions; Pain
|
|
| ALT_DEFINITION |
A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin.
|
|
| CAS_Registry |
54-21-7
|
|
| Chemical_Formula |
C7H5O3.Na
|
|
| code |
C834
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC
|
|
| DEFINITION |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04)
|
|
| FDA_UNII_Code |
WIQ1H85SYP
|
|
| FULL_SYN |
sodium salicylate Salicylate, sodium Sodium Salicylate Benzoic acid, 2-hydroxy-, monosodium salt Sodium salicylate SODIUM SALICYLATE
|
|
| Is_Value_For_GDC_Property | ||
| label |
Sodium Salicylate
|
|
| Legacy Concept Name |
Sodium_Salicylate
|
|
| Maps_To |
Sodium Salicylate
|
|
| NCI_Drug_Dictionary_ID |
43094
|
|
| NSC Number |
202167
|
|
| PDQ_Closed_Trial_Search_ID |
43094
|
|
| PDQ_Open_Trial_Search_ID |
43094
|
|
| Preferred_Name |
Sodium Salicylate
|
|
| prefixIRI |
Thesaurus:C834
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0037549
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |