loading...| Preferred Name |
Sodium Salicylate |
|
| Synonyms |
sodium salicylate Salicylate, sodium Sodium Salicylate Benzoic acid, 2-hydroxy-, monosodium salt Sodium salicylate SODIUM SALICYLATE |
|
| Definitions |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C834 |
|
| Accepted_Therapeutic_Use_For |
Fever; Inflammatory conditions; Pain |
|
| ALT_DEFINITION |
A drug that is a type of nonsteroidal anti-inflammatory drug. Sodium salicylate may be tolerated by people who are sensitive to aspirin. |
|
| CAS_Registry |
54-21-7 |
|
| Chemical_Formula |
C7H5O3.Na |
|
| code |
C834 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
FDA GDC |
|
| DEFINITION |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. (NCI04) |
|
| FDA_UNII_Code |
WIQ1H85SYP |
|
| FULL_SYN |
sodium salicylate Salicylate, sodium Sodium Salicylate Benzoic acid, 2-hydroxy-, monosodium salt Sodium salicylate SODIUM SALICYLATE |
|
| Is_Value_For_GDC_Property | ||
| label |
Sodium Salicylate |
|
| Legacy Concept Name |
Sodium_Salicylate |
|
| Maps_To |
Sodium Salicylate |
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| NCI_Drug_Dictionary_ID |
43094 |
|
| NSC Number |
202167 |
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| PDQ_Closed_Trial_Search_ID |
43094 |
|
| PDQ_Open_Trial_Search_ID |
43094 |
|
| Preferred_Name |
Sodium Salicylate |
|
| prefixIRI |
Thesaurus:C834 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0037549 |
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| subClassOf |