National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Telaprevir
Synonyms

Incivek

LY-570310

MP-424

TELAPREVIR

Telaprevir

VRT-111950

VX-950

Definitions

An orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81603

Accepted_Therapeutic_Use_For

Chronic Hepatitis C

CAS_Registry

402957-28-2

Chemical_Formula

C36H53N7O6

code

C81603

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

An orally available peptidomimetic small molecule with activity against hepatitis C virus (HCV). Telaprivir is a selective protease inhibitor that targets the viral HCV NS3-4A serine protease and disrupts processing of viral proteins and formation of a viral replication complex.

Display_Name

Telaprevir

FDA_UNII_Code

655M5O3W0U

FULL_SYN

Incivek

LY-570310

MP-424

TELAPREVIR

Telaprevir

VRT-111950

VX-950

label

Telaprevir

Legacy Concept Name

Telaprevir

NCI_Drug_Dictionary_ID

748913

PDQ_Closed_Trial_Search_ID

748913

PDQ_Open_Trial_Search_ID

748913

Preferred_Name

Telaprevir

prefixIRI

Thesaurus:C81603

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1876229

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C281

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C783

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