National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Saxagliptin

Synonyms

Saxagliptin Monohydrate

Saxagliptin Hydrate

SAXAGLIPTIN

BMS-477118-11

Saxagliptin

Definitions

A potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75983

CAS_Registry

945667-22-1

Chemical_Formula

C18H25N3O2.H2O

code

C75983

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.

FDA_UNII_Code

9GB927LAJW

FULL_SYN

Saxagliptin Monohydrate

Saxagliptin Hydrate

SAXAGLIPTIN

BMS-477118-11

Saxagliptin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81702

label

Saxagliptin

Legacy Concept Name

Saxagliptin

NSC Number

760407

Preferred_Name

Saxagliptin

prefixIRI

Thesaurus:C75983

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1611934

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98086

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