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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Saxagliptin | |
| Synonyms |
Saxagliptin Monohydrate Saxagliptin Hydrate SAXAGLIPTIN BMS-477118-11 Saxagliptin |
|
| Definitions |
A potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75983 |
|
| CAS_Registry |
945667-22-1
|
|
| Chemical_Formula |
C18H25N3O2.H2O
|
|
| code |
C75983
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A potent, selective and competitive, cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.
|
|
| FDA_UNII_Code |
9GB927LAJW
|
|
| FULL_SYN |
Saxagliptin Monohydrate Saxagliptin Hydrate SAXAGLIPTIN BMS-477118-11 Saxagliptin
|
|
| Has_Salt_Form | ||
| label |
Saxagliptin
|
|
| Legacy Concept Name |
Saxagliptin
|
|
| NSC Number |
760407
|
|
| Preferred_Name |
Saxagliptin
|
|
| prefixIRI |
Thesaurus:C75983
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1611934
|
|
| subClassOf |
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