National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Localized Scleroderma

Synonyms

Localized Scleroderma

Localized scleroderma [morphea]

Morphea

Definitions

A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72069

ALT_DEFINITION

An autoimmune disorder marked by excessive production of collagen resulting in hardening and thickening of skin, with formation of patches or lines of thick and unyielding tissue. There can also be musculoskeletal and underlying tissue involvement. The affected areas of skin can be restrictive and disfiguring.

code

C72069

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193205

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193006

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

Contributing_Source

Cellosaurus

CTRP

MedDRA

NICHD

mCode

DEFINITION

A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types.

Display_Name

Localized Scleroderma

FULL_SYN

Localized Scleroderma

Localized scleroderma [morphea]

Morphea

label

Localized Scleroderma

Legacy Concept Name

Localized_Scleroderma

Maps_To

Morphea

Preferred_Name

Localized Scleroderma

prefixIRI

Thesaurus:C72069

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0036420

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26746

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