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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Nystatin | |
| Synonyms |
Mycostatin NYSTATIN Nystatin Nystex mycostatin nystatin |
|
| Definitions |
A polyene macrolide antibiotic, with antifungal activity. Upon administration, nystatin binds to sterols in the fungal plasma membrane, thereby increasing membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually fungal cell death. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C710 |
|
| ALT_DEFINITION |
The active ingredient in a drug used to treat infections caused by fungi (a type of microorganism). Nystatin is made by certain strains of bacteria and kills fungi by binding to their membranes. It is a type of antifungal agent.
|
|
| CAS_Registry |
1400-61-9
|
|
| CHEBI_ID |
CHEBI:7660
|
|
| code |
C710
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
FDA HemOnc
|
|
| DEFINITION |
A polyene macrolide antibiotic, with antifungal activity. Upon administration, nystatin binds to sterols in the fungal plasma membrane, thereby increasing membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually fungal cell death.
|
|
| FDA_UNII_Code |
BDF1O1C72E
|
|
| FULL_SYN |
Mycostatin NYSTATIN Nystatin Nystex mycostatin nystatin
|
|
| label |
Nystatin
|
|
| Legacy Concept Name |
Nystatin
|
|
| NCI_Drug_Dictionary_ID |
39512
|
|
| NSC Number |
150817
|
|
| PDQ_Closed_Trial_Search_ID |
39512
|
|
| PDQ_Open_Trial_Search_ID |
39512
|
|
| Preferred_Name |
Nystatin
|
|
| prefixIRI |
Thesaurus:C710
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0028741
|
|
| subClassOf |
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