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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Tolbutamide | |
| Synonyms |
Tolbutamide TOLBUTAMIDE N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide |
|
| Definitions |
A short-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to second-generation sulfonylureas, tolbutamide is more likely to cause adverse effects, such as jaundice. This agent is rapidly metabolized by CYPC29. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66610 |
|
| CAS_Registry |
64-77-7
|
|
| CHEBI_ID |
CHEBI:27999
|
|
| Chemical_Formula |
C12H18N2O3S
|
|
| code |
C66610
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A short-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to second-generation sulfonylureas, tolbutamide is more likely to cause adverse effects, such as jaundice. This agent is rapidly metabolized by CYPC29.
|
|
| Display_Name |
Tolbutamide
|
|
| FDA_UNII_Code |
982XCM1FOI
|
|
| FULL_SYN |
Tolbutamide TOLBUTAMIDE N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide
|
|
| Has_Salt_Form | ||
| label |
Tolbutamide
|
|
| Legacy Concept Name |
Tolbutamide
|
|
| NCI_Drug_Dictionary_ID |
684270
|
|
| PDQ_Closed_Trial_Search_ID |
684270
|
|
| PDQ_Open_Trial_Search_ID |
684270
|
|
| Preferred_Name |
Tolbutamide
|
|
| prefixIRI |
Thesaurus:C66610
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0040374
|
|
| subClassOf |
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