National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Oxyphencyclimine Hydrochloride

Synonyms

OXYPHENCYCLIMINE HYDROCHLORIDE

Oxyphencyclimine Hydrochloride

Definitions

The hydrochloride salt form of oxyphencyclimine, a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Oxyphencyclimine binds to and blocks the muscarinic receptor on smooth muscle. This agent has a direct relaxing effect on smooth muscle and therefore prevents spasms in the muscles of the gastrointestinal tract, inhibits gastrointestinal propulsive motility, decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretion.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66284

CAS_Registry

125-52-0

Chemical_Formula

C20H28N2O3.HCl

code

C66284

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of oxyphencyclimine, a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Oxyphencyclimine binds to and blocks the muscarinic receptor on smooth muscle. This agent has a direct relaxing effect on smooth muscle and therefore prevents spasms in the muscles of the gastrointestinal tract, inhibits gastrointestinal propulsive motility, decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretion.

FDA_UNII_Code

GWO1432WOU

FULL_SYN

OXYPHENCYCLIMINE HYDROCHLORIDE

Oxyphencyclimine Hydrochloride

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66283

label

Oxyphencyclimine Hydrochloride

Legacy Concept Name

Oxyphencyclimine_Hydrochloride

Preferred_Name

Oxyphencyclimine Hydrochloride

prefixIRI

Thesaurus:C66284

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0304424

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29698

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29704

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