loading...| Preferred Name |
Isoetharine |
|
| Synonyms |
ISOETHARINE Isoetharine |
|
| Definitions |
A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65974 |
|
| CAS_Registry |
530-08-5 |
|
| Chemical_Formula |
C13H21NO3 |
|
| code |
C65974 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
|
| FDA_UNII_Code |
YV0SN3276Q |
|
| FULL_SYN |
ISOETHARINE Isoetharine |
|
| Has_Salt_Form | ||
| label |
Isoetharine |
|
| Legacy Concept Name |
Isoetharine |
|
| Preferred_Name |
Isoetharine |
|
| prefixIRI |
Thesaurus:C65974 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0022176 |
|
| subClassOf |