Preferred Name |
Hetacillin Potassium |
|
Synonyms |
Hetacillin Potassium HETACILLIN POTASSIUM |
|
Definitions |
The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65845 |
|
CAS_Registry |
5321-32-4 |
|
CHEBI_ID |
CHEBI:34789 |
|
Chemical_Formula |
C19H22N3O4S.K |
|
code |
C65845 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
FDA_UNII_Code |
95PFX5932Y |
|
FULL_SYN |
Hetacillin Potassium HETACILLIN POTASSIUM |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Hetacillin Potassium |
|
Legacy Concept Name |
Hetacillin_Potassium |
|
Preferred_Name |
Hetacillin Potassium |
|
prefixIRI |
Thesaurus:C65845 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0812398 |
|
subClassOf |