loading...| Preferred Name |
Ciclopirox Olamine |
|
| Synonyms |
Ciclopirox Olamine CICLOPIROX OLAMINE |
|
| Definitions |
The olamine salt form of ciclopirox, a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65327 |
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| CAS_Registry |
41621-49-2 |
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| CHEBI_ID |
CHEBI:31398 |
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| Chemical_Formula |
C12H17NO2.C2H7NO |
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| code |
C65327 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The olamine salt form of ciclopirox, a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). |
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| FDA_UNII_Code |
50MD4SB4AP |
|
| FULL_SYN |
Ciclopirox Olamine CICLOPIROX OLAMINE |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Ciclopirox Olamine |
|
| Legacy Concept Name |
Ciclopirox_Olamine |
|
| Preferred_Name |
Ciclopirox Olamine |
|
| prefixIRI |
Thesaurus:C65327 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0126169 |
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| subClassOf |