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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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Preferred Name | Cefmetazole Sodium | |
Synonyms |
Cefmetazole Sodium CEFMETAZOLE SODIUM |
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Definitions |
The sodium salt form of cefmetazole, a second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65298 |
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CAS_Registry |
56796-39-5
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CHEBI_ID |
CHEBI:3490
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Chemical_Formula |
C15H16N7O5S3.Na
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code |
C65298
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Concept_In_Subset | ||
Contributing_Source |
FDA
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DEFINITION |
The sodium salt form of cefmetazole, a second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
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FDA_UNII_Code |
37Y9VR4W7A
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FULL_SYN |
Cefmetazole Sodium CEFMETAZOLE SODIUM
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Has_Free_Acid_Or_Base_Form | ||
label |
Cefmetazole Sodium
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Legacy Concept Name |
Cefmetazole_Sodium
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NCI_Drug_Dictionary_ID |
564415
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PDQ_Closed_Trial_Search_ID |
564415
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PDQ_Open_Trial_Search_ID |
564415
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Preferred_Name |
Cefmetazole Sodium
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prefixIRI |
Thesaurus:C65298
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0700470
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subClassOf |
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