National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Cefmetazole Sodium
Synonyms

Cefmetazole Sodium

CEFMETAZOLE SODIUM

Definitions

The sodium salt form of cefmetazole, a second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65298

CAS_Registry

56796-39-5

CHEBI_ID

CHEBI:3490

Chemical_Formula

C15H16N7O5S3.Na

code

C65298

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The sodium salt form of cefmetazole, a second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

FDA_UNII_Code

37Y9VR4W7A

FULL_SYN

Cefmetazole Sodium

CEFMETAZOLE SODIUM

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65297

label

Cefmetazole Sodium

Legacy Concept Name

Cefmetazole_Sodium

NCI_Drug_Dictionary_ID

564415

PDQ_Closed_Trial_Search_ID

564415

PDQ_Open_Trial_Search_ID

564415

Preferred_Name

Cefmetazole Sodium

prefixIRI

Thesaurus:C65298

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0700470

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C357

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