National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Brimonidine

Synonyms

BRIMONIDINE

Brimonidine

Brimodine

Definitions

An imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine also enhances the uveoscleral outflow of aqueous humor. This reduces intraocular pressure.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65269

CAS_Registry

59803-98-4

CHEBI_ID

CHEBI:3175

Chemical_Formula

C11H10BrN5

code

C65269

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine also enhances the uveoscleral outflow of aqueous humor. This reduces intraocular pressure.

FDA_UNII_Code

E6GNX3HHTE

FULL_SYN

BRIMONIDINE

Brimonidine

Brimodine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158723

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47419

label

Brimonidine

Legacy Concept Name

Brimonidine

Preferred_Name

Brimonidine

prefixIRI

Thesaurus:C65269

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0525227

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29705

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