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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Brimonidine | |
| Synonyms |
BRIMONIDINE Brimonidine Brimodine |
|
| Definitions |
An imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine also enhances the uveoscleral outflow of aqueous humor. This reduces intraocular pressure. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65269 |
|
| CAS_Registry |
59803-98-4
|
|
| CHEBI_ID |
CHEBI:3175
|
|
| Chemical_Formula |
C11H10BrN5
|
|
| code |
C65269
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
An imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine also enhances the uveoscleral outflow of aqueous humor. This reduces intraocular pressure.
|
|
| FDA_UNII_Code |
E6GNX3HHTE
|
|
| FULL_SYN |
BRIMONIDINE Brimonidine Brimodine
|
|
| Has_Salt_Form | ||
| label |
Brimonidine
|
|
| Legacy Concept Name |
Brimonidine
|
|
| Preferred_Name |
Brimonidine
|
|
| prefixIRI |
Thesaurus:C65269
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0525227
|
|
| subClassOf |
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