loading...| Preferred Name |
Beta-2-Microglobulin |
|
| Synonyms |
Beta-2 Microglobulin beta-2-microglobulin Beta-2-Microglobulin Beta-2-Microglobin B2M |
|
| Definitions |
Beta-2-microglobulin protein (119 aa, ~14 kDa) is encoded by the human B2M gene. This protein plays a role in immune responses and is a key component of major histocompatibility complex class I molecules. The protein is localized to the surface of cells and is utilized as a prognostic marker in persons with cancers that involve white blood cells. The polypeptide is also used as a marker in kidney damage diagnosis and in the detection of viral infection. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62657 |
|
| ALT_DEFINITION |
A small protein normally found on the surface of many cells, including lymphocytes, and in small amounts in the blood and urine. An increased amount in the blood or urine may be a sign of certain diseases, including some types of cancer, such as multiple myeloma or lymphoma. |
|
| code |
C62657 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Beta-2-microglobulin protein (119 aa, ~14 kDa) is encoded by the human B2M gene. This protein plays a role in immune responses and is a key component of major histocompatibility complex class I molecules. The protein is localized to the surface of cells and is utilized as a prognostic marker in persons with cancers that involve white blood cells. The polypeptide is also used as a marker in kidney damage diagnosis and in the detection of viral infection. |
|
| Display_Name |
Beta-2-Microglobulin |
|
| FULL_SYN |
Beta-2 Microglobulin beta-2-microglobulin Beta-2-Microglobulin Beta-2-Microglobin B2M |
|
| label |
Beta-2-Microglobulin |
|
| Legacy Concept Name |
Beta-2-Microglobulin_Protein |
|
| NCI_META_CUI |
CL1374571 |
|
| OMIM_Number |
109700 |
|
| Preferred_Name |
Beta-2-Microglobulin |
|
| prefixIRI |
Thesaurus:C62657 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Biologically Active Substance |
|
| Swiss_Prot |
Q540F8 |
|
| subClassOf |