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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Tazobactam | |
| Synonyms |
(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide TAZOBACTAM Tazobactam YTR-830H |
|
| Definitions |
A penicillanic acid sulfone derivative and beta-lactamase inhibitor with antibacterial activity. Tazobactam contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62079 |
|
| CAS_Registry |
89786-04-9
|
|
| Chemical_Formula |
C10H12N4O5S
|
|
| code |
C62079
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A penicillanic acid sulfone derivative and beta-lactamase inhibitor with antibacterial activity. Tazobactam contains a beta-lactam ring and irreversibly binds to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms.
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|
| Display_Name |
Tazobactam
|
|
| FDA_UNII_Code |
SE10G96M8W
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|
| FULL_SYN |
(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 4,4-dioxide TAZOBACTAM Tazobactam YTR-830H
|
|
| Has_Salt_Form | ||
| label |
Tazobactam
|
|
| Legacy Concept Name |
Tazobactam_Base
|
|
| Preferred_Name |
Tazobactam
|
|
| prefixIRI |
Thesaurus:C62079
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
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|
| UMLS_CUI |
C0075870
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|
| subClassOf |
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