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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Oxacillin | |
| Synonyms |
OXACILLIN Oxacillin |
|
| Definitions |
A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62063 |
|
| CAS_Registry |
66-79-5
|
|
| CHEBI_ID |
CHEBI:7809
|
|
| Chemical_Formula |
C19H19N3O5S
|
|
| code |
C62063
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis.
|
|
| Display_Name |
Oxacillin
|
|
| FDA_UNII_Code |
UH95VD7V76
|
|
| FULL_SYN |
OXACILLIN Oxacillin
|
|
| Has_Salt_Form | ||
| label |
Oxacillin
|
|
| Legacy Concept Name |
Oxacillin_Base
|
|
| Preferred_Name |
Oxacillin
|
|
| prefixIRI |
Thesaurus:C62063
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0029983
|
|
| subClassOf |
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