National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Buspirone
Synonyms

BUSPIRONE

Buspirone

buspirone

Definitions

An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62013

ALT_DEFINITION

A drug that is used to treat certain anxiety disorders. It belongs to the family of drugs called antianxiety agents.

CAS_Registry

36505-84-7

CHEBI_ID

CHEBI:3223

Chemical_Formula

C21H31N5O2

code

C62013

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.

FDA_UNII_Code

TK65WKS8HL

FULL_SYN

BUSPIRONE

Buspirone

buspirone

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26641

label

Buspirone

Legacy Concept Name

Buspirone_Base

Preferred_Name

Buspirone

prefixIRI

Thesaurus:C62013

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0006462

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28197

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/NCIT_C62013 BERO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Buspirone APAONTO LOOM
http://purl.obolibrary.org/obo/MESH_D002065 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 OBA LOOM
http://purl.bioontology.org/ontology/CSP/4000-0133 CRISP LOOM
http://purl.bioontology.org/ontology/VANDF/4019646 VANDF LOOM
http://purl.jp/bio/4/id/200906092539845452 IOBC LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass4f27d3a3_7013_4343_bce6_115918d87f26 WWECA LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2244 OCHV LOOM
http://www.drugbank.ca/drugs/DB00490 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387523009 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Buspirone GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016975 PMAPP-PMO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147739 ODAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.885.120 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907031039222429 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0003414 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.120 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00490 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.885.120 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU063033 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006462 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/N05BE01 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147739 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-64210 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002065 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP17859-7 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/1827 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D002065 MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004586 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/x01BH RCD LOOM