loading...| Preferred Name |
Beclomethasone |
|
| Synonyms |
(11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione BECLOMETHASONE Beclomethasone beclomethasone |
|
| Definitions |
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62009 |
|
| ALT_DEFINITION |
A drug being studied in the treatment of graft-versus-host disease. It belongs to a family of drugs called corticosteroids. |
|
| CAS_Registry |
4419-39-0 |
|
| CHEBI_ID |
CHEBI:3001 |
|
| Chemical_Formula |
C22H29ClO5 |
|
| code |
C62009 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
| FDA_UNII_Code |
KGZ1SLC28Z |
|
| FULL_SYN |
(11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione BECLOMETHASONE Beclomethasone beclomethasone |
|
| label |
Beclomethasone |
|
| Legacy Concept Name |
Beclomethasone_Base |
|
| Preferred_Name |
Beclomethasone |
|
| prefixIRI |
Thesaurus:C62009 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0004905 |
|
| subClassOf |