loading...| Preferred Name |
Pirbuterol |
|
| Synonyms |
PIRBUTEROL Pirbuterol |
|
| Definitions |
A short-acting, beta-adrenergic receptor agonist with bronchodilator activity. Pirbuterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61893 |
|
| CAS_Registry |
38677-81-5 |
|
| Chemical_Formula |
C12H20N2O3 |
|
| code |
C61893 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A short-acting, beta-adrenergic receptor agonist with bronchodilator activity. Pirbuterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells. |
|
| FDA_UNII_Code |
OG645J8RVW |
|
| FULL_SYN |
PIRBUTEROL Pirbuterol |
|
| Has_Salt_Form | ||
| label |
Pirbuterol |
|
| Legacy Concept Name |
Pirbuterol |
|
| Preferred_Name |
Pirbuterol |
|
| prefixIRI |
Thesaurus:C61893 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0071129 |
|
| subClassOf |