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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Phentermine | |
| Synonyms |
Phentermine 2-Phenyl-tert-butylamine PHENTERMINE 1,1-Dimethyl-2-phenylethylamine 2-Amino-2-methyl-1-phenylpropane |
|
| Definitions |
A natural monoamine alkaloid derivative and a sympathomimetic stimulant with appetite suppressant property. Phentermine, which was part of the Fen-Phen anti-obesity medication, stimulates hypothalamic release of norepinephrine, a neurotransmitter involved in stress responses (fight-or-flight reactions), and reduces hunger sensation. Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61890 |
|
| CAS_Registry |
122-09-8
|
|
| CHEBI_ID |
CHEBI:8080
|
|
| Chemical_Formula |
C10H15N
|
|
| code |
C61890
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A natural monoamine alkaloid derivative and a sympathomimetic stimulant with appetite suppressant property. Phentermine, which was part of the Fen-Phen anti-obesity medication, stimulates hypothalamic release of norepinephrine, a neurotransmitter involved in stress responses (fight-or-flight reactions), and reduces hunger sensation. Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat.
|
|
| FDA_UNII_Code |
C045TQL4WP
|
|
| FULL_SYN |
Phentermine 2-Phenyl-tert-butylamine PHENTERMINE 1,1-Dimethyl-2-phenylethylamine 2-Amino-2-methyl-1-phenylpropane
|
|
| Has_Salt_Form | ||
| label |
Phentermine
|
|
| Legacy Concept Name |
Phentermine
|
|
| Preferred_Name |
Phentermine
|
|
| prefixIRI |
Thesaurus:C61890
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0031447
|
|
| subClassOf |
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