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National Cancer Institute Thesaurus
| Preferred Name | Paromomycin | |
| Synonyms |
O-2,6-Diamino-2,6-Dideoxy-Beta-L-Idopyranosyl-(1->3)-O-Beta-D-Ribofuranosyl-(1->5)-O-(2-Amino-2-Deoxy-Alpha-D-Glucopyranosyl-(1->4))-2-Deoxystreptamine Hydroxymycin Antibiotic SF 767B PAROMOMYCIN Paromomycin I Paromomycin Monomycin A Antibiotic 503-3 Quintomycin C O-2-Amino-2-Deoxy-Alpha-D-Glucopyranosyl-(1->4)-O-(O-2,6-Diamino-2,6-Dideoxy-Beta-L-Idopyranosyl-(1->3)-Beta-D-Ribofuranosyl-(1->5))-2-Deoxy-D-Streptamine Estomycin Gabromycin Neomycin E Paucimycin R-400 |
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| Definitions |
An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61878 |
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| CAS_Registry |
59-04-1 7542-37-2
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| CHEBI_ID |
CHEBI:7934
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| Chemical_Formula |
C23H45N5O14
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|
| code |
C61878
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death.
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| FDA_UNII_Code |
61JJC8N5ZK
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| FULL_SYN |
O-2,6-Diamino-2,6-Dideoxy-Beta-L-Idopyranosyl-(1->3)-O-Beta-D-Ribofuranosyl-(1->5)-O-(2-Amino-2-Deoxy-Alpha-D-Glucopyranosyl-(1->4))-2-Deoxystreptamine Hydroxymycin Antibiotic SF 767B PAROMOMYCIN Paromomycin I Paromomycin Monomycin A Antibiotic 503-3 Quintomycin C O-2-Amino-2-Deoxy-Alpha-D-Glucopyranosyl-(1->4)-O-(O-2,6-Diamino-2,6-Dideoxy-Beta-L-Idopyranosyl-(1->3)-Beta-D-Ribofuranosyl-(1->5))-2-Deoxy-D-Streptamine Estomycin Gabromycin Neomycin E Paucimycin R-400
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|
| Has_Salt_Form | ||
| label |
Paromomycin
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|
| Legacy Concept Name |
Paromomycin
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|
| Preferred_Name |
Paromomycin
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| prefixIRI |
Thesaurus:C61878
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0030576
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| subClassOf |
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