National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Oleandomycin
Synonyms

OLEANDOMYCIN

Oleandomycin

Definitions

A macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61864

CAS_Registry

3922-90-5

CHEBI_ID

CHEBI:16869

Chemical_Formula

C35H61NO12

code

C61864

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.

FDA_UNII_Code

P8ZQ646136

FULL_SYN

OLEANDOMYCIN

Oleandomycin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61865

label

Oleandomycin

Legacy Concept Name

Oleandomycin

Preferred_Name

Oleandomycin

prefixIRI

Thesaurus:C61864

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0028923

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C261

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_16869 DRON LOOM
http://purl.obolibrary.org/obo/ARO_3000867 ARO LOOM
http://purl.bioontology.org/ontology/ATC/J01FA05 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008464 LOINC LOOM
http://purl.bioontology.org/ontology/NDDF/002764 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009827 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907050173477829 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/7629 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_16869 GENEPIO LOOM
http://purl.obolibrary.org/obo/OMIT_0010842 OMIT LOOM
https://go.drugbank.com/drugs/DB11442 MDM LOOM
http://purl.jp/bio/4/id/200906087578493683 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP16195-7 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/D009827 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017164 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/41332001 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.540.505.600 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C61864 BERO LOOM
http://purl.obolibrary.org/obo/MESH_D009827 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-522B9 SNMI LOOM