loading...| Preferred Name |
Lomefloxacin |
|
| Synonyms |
Lomefloxacin LOMEFLOXACIN |
|
| Definitions |
A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61814 |
|
| CAS_Registry |
98079-51-7 |
|
| CHEBI_ID |
CHEBI:116278 |
|
| Chemical_Formula |
C17H19F2N3O3 |
|
| code |
C61814 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| FDA_UNII_Code |
L6BR2WJD8V |
|
| FULL_SYN |
Lomefloxacin LOMEFLOXACIN |
|
| Has_Salt_Form | ||
| label |
Lomefloxacin |
|
| Legacy Concept Name |
Lomefloxacin |
|
| Preferred_Name |
Lomefloxacin |
|
| prefixIRI |
Thesaurus:C61814 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0065162 |
|
| subClassOf |