National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Lodoxamide

Synonyms

LODOXAMIDE

Lodoxamide

Definitions

A synthetic mast cell stabilizing compound with anti-inflammatory activity. Lodoxamide appears to inhibit the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell degranulation and the release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions. Lodoxamide also inhibits eosinophil chemotaxis. When applied topically to the eye, this drug prevents the symptoms associated with keratitis or conjunctivitis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61813

CAS_Registry

53882-12-5

Chemical_Formula

C11H6ClN3O6

code

C61813

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic mast cell stabilizing compound with anti-inflammatory activity. Lodoxamide appears to inhibit the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell degranulation and the release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions. Lodoxamide also inhibits eosinophil chemotaxis. When applied topically to the eye, this drug prevents the symptoms associated with keratitis or conjunctivitis.

FDA_UNII_Code

SPU695OD73

FULL_SYN

LODOXAMIDE

Lodoxamide

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29160

label

Lodoxamide

Legacy Concept Name

Lodoxamide

Preferred_Name

Lodoxamide

prefixIRI

Thesaurus:C61813

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0126120

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29714

Delete Subject Author Type Created
No notes to display