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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ketotifen | |
| Synonyms |
Alaway KETOTIFEN Ketotifen |
|
| Definitions |
A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799 |
|
| CAS_Registry |
34580-13-7
|
|
| Chemical_Formula |
C19H19NOS
|
|
| code |
C61799
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 |
|
| Contributing_Source |
FDA
|
|
| DEFINITION |
A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.
|
|
| FDA_UNII_Code |
X49220T18G
|
|
| FULL_SYN |
Alaway KETOTIFEN Ketotifen
|
|
| Has_Salt_Form | ||
| label |
Ketotifen
|
|
| Legacy Concept Name |
Ketotifen
|
|
| Preferred_Name |
Ketotifen
|
|
| prefixIRI |
Thesaurus:C61799
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0022642
|
|
| subClassOf |
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