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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Imipramine Pamoate | |
| Synonyms |
IMIPRAMINE PAMOATE Imipramine Pamoate Tofranil-PM |
|
| Definitions |
The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin, thereby preventing their degradation and increasing their availability. This drug also has antimuscarinic and anti-histamine properties, which contribute to its side effects. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61788 |
|
| CAS_Registry |
10075-24-8 22540-17-6
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|
| Chemical_Formula |
C23H16O6.2C19H24N2
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|
| code |
C61788
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|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin, thereby preventing their degradation and increasing their availability. This drug also has antimuscarinic and anti-histamine properties, which contribute to its side effects.
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| FDA_UNII_Code |
MC34P30298
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|
| FULL_SYN |
IMIPRAMINE PAMOATE Imipramine Pamoate Tofranil-PM
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|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Imipramine Pamoate
|
|
| Legacy Concept Name |
Imipramine_Pamoate
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|
| Preferred_Name |
Imipramine Pamoate
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|
| prefixIRI |
Thesaurus:C61788
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0304368
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| subClassOf |
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