loading...| Preferred Name |
Fenoprofen Calcium |
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| Synonyms |
Fenoprofen Calcium Dihydrate FENOPROFEN CALCIUM Fenoprofen Calcium |
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| Definitions |
The calcium salt form of fenoprofen, a propionic acid derivative with analgesic, non-steroidal antiinflammatory and antirheumatic properties. Fenoprofen inhibits both isozymes of cyclooxygenase; resulting in prostaglandin synthesis inhibition, thereby blocking the conversion of arachidonic acid to prostaglandins. In addition, fenoprofen activate both peroxisome proliferator activated receptors (PPAR)-alpha and -gamma, by which it may down-regulate leukotriene B4 production. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61761 |
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| CAS_Registry |
53746-45-5 |
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| CHEBI_ID |
CHEBI:5005 |
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| Chemical_Formula |
2C15H13O3.Ca.2H2O |
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| code |
C61761 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The calcium salt form of fenoprofen, a propionic acid derivative with analgesic, non-steroidal antiinflammatory and antirheumatic properties. Fenoprofen inhibits both isozymes of cyclooxygenase; resulting in prostaglandin synthesis inhibition, thereby blocking the conversion of arachidonic acid to prostaglandins. In addition, fenoprofen activate both peroxisome proliferator activated receptors (PPAR)-alpha and -gamma, by which it may down-regulate leukotriene B4 production. |
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| FDA_UNII_Code |
0X2CW1QABJ |
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| FULL_SYN |
Fenoprofen Calcium Dihydrate FENOPROFEN CALCIUM Fenoprofen Calcium |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Fenoprofen Calcium |
|
| Legacy Concept Name |
Fenoprofen_Calcium |
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| Preferred_Name |
Fenoprofen Calcium |
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| prefixIRI |
Thesaurus:C61761 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0887323 |
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| subClassOf |