Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Desvenlafaxine Succinate | |
| Synonyms |
DESVENLAFAXINE SUCCINATE Desvenlafaxine Succinate Butanedioic Acid, Compound With 4-(2-(Dimethylamino)-1-(1-Hydroxycyclohexyl)Ethyl)Phenol (1:1), Monohydrate Pristiq |
|
| Definitions |
The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61704 |
|
| CAS_Registry |
386750-22-7
|
|
| Chemical_Formula |
C16H25NO2.C4H6O4.H2O
|
|
| code |
C61704
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state.
|
|
| FDA_UNII_Code |
ZB22ENF0XR
|
|
| FULL_SYN |
DESVENLAFAXINE SUCCINATE Desvenlafaxine Succinate Butanedioic Acid, Compound With 4-(2-(Dimethylamino)-1-(1-Hydroxycyclohexyl)Ethyl)Phenol (1:1), Monohydrate Pristiq
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Desvenlafaxine Succinate
|
|
| Legacy Concept Name |
Desvenlafaxine_Succinate
|
|
| NCI_Drug_Dictionary_ID |
747472
|
|
| PDQ_Closed_Trial_Search_ID |
747472
|
|
| PDQ_Open_Trial_Search_ID |
747472
|
|
| Preferred_Name |
Desvenlafaxine Succinate
|
|
| prefixIRI |
Thesaurus:C61704
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1742884
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping