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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Desvenlafaxine | |
| Synonyms |
Desvenlafaxine DESVENLAFAXINE |
|
| Definitions |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61703 |
|
| CAS_Registry |
93413-62-8
|
|
| Chemical_Formula |
C16H25NO2
|
|
| code |
C61703
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state.
|
|
| FDA_UNII_Code |
NG99554ANW
|
|
| FULL_SYN |
Desvenlafaxine DESVENLAFAXINE
|
|
| Has_Salt_Form | ||
| label |
Desvenlafaxine
|
|
| Legacy Concept Name |
Desvenlafaxine
|
|
| Preferred_Name |
Desvenlafaxine
|
|
| prefixIRI |
Thesaurus:C61703
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1289960
|
|
| subClassOf |
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