Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Cefotetan | |
| Synonyms |
ICI 156,834 CEFOTETAN Cefotetan ICI-156834 |
|
| Definitions |
A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61664 |
|
| CAS_Registry |
69712-56-7
|
|
| CHEBI_ID |
CHEBI:3499
|
|
| Chemical_Formula |
C17H17N7O8S4
|
|
| code |
C61664
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins.
|
|
| FDA_UNII_Code |
48SPP0PA9Q
|
|
| FULL_SYN |
ICI 156,834 CEFOTETAN Cefotetan ICI-156834
|
|
| Has_Salt_Form | ||
| label |
Cefotetan
|
|
| Legacy Concept Name |
Cefotetan
|
|
| Preferred_Name |
Cefotetan
|
|
| prefixIRI |
Thesaurus:C61664
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0007555
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping