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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Alfentanil | |
| Synonyms |
ALFENTANIL Alfentanil |
|
| Definitions |
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61626 |
|
| CAS_Registry |
71195-58-9
|
|
| CHEBI_ID |
CHEBI:2569
|
|
| Chemical_Formula |
C21H32N6O3
|
|
| code |
C61626
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.
|
|
| FDA_UNII_Code |
1N74HM2BS7
|
|
| FULL_SYN |
ALFENTANIL Alfentanil
|
|
| Has_Salt_Form | ||
| label |
Alfentanil
|
|
| Legacy Concept Name |
Alfentanil
|
|
| Preferred_Name |
Alfentanil
|
|
| prefixIRI |
Thesaurus:C61626
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0002026
|
|
| subClassOf |
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