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National Cancer Institute Thesaurus
| Preferred Name | Apixaban | |
| Synonyms |
1H-Pyrazolo(3,4-c)pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)- BMS-562247-01 APIXABAN Apixaban BMS-562247 Eliquis |
|
| Definitions |
An orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61308 |
|
| CAS_Registry |
503612-47-3
|
|
| Chemical_Formula |
C25H25N5O4
|
|
| code |
C61308
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
| Contributing_Source |
CTRP FDA HemOnc
|
|
| DEFINITION |
An orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots.
|
|
| Display_Name |
Apixaban
|
|
| FDA_UNII_Code |
3Z9Y7UWC1J
|
|
| FULL_SYN |
1H-Pyrazolo(3,4-c)pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)- BMS-562247-01 APIXABAN Apixaban BMS-562247 Eliquis
|
|
| label |
Apixaban
|
|
| Legacy Concept Name |
Apixaban
|
|
| NCI_Drug_Dictionary_ID |
484444
|
|
| PDQ_Closed_Trial_Search_ID |
484444
|
|
| PDQ_Open_Trial_Search_ID |
484444
|
|
| Preferred_Name |
Apixaban
|
|
| prefixIRI |
Thesaurus:C61308
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1831808
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| subClassOf |
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