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National Cancer Institute Thesaurus
| Preferred Name | Levamisole Hydrochloride | |
| Synonyms |
Cloridrato de Levamizol (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Monohydrochloride l-Tetramisole Hydrochloride Levamisole Hydrochloride LEVAMISOLE HYDROCHLORIDE l-Tetramisole hydrochloride Ascaridil Decaris Ergamisol Ergamisole ICI-59623 Immunol Ketrax R 12564 R-12564 RP-20605 Solaskil Tramisol Trimisol |
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| Definitions |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C610 |
|
| Accepted_Therapeutic_Use_For |
Stage III Colon Cancer
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|
| CAS_Registry |
16595-80-5
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|
| Chemical_Formula |
C11H12N2S.HCl
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|
| code |
C610
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis.
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|
| Display_Name |
Levamisole Hydrochloride
|
|
| FDA_UNII_Code |
DL9055K809
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|
| FULL_SYN |
Cloridrato de Levamizol (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Monohydrochloride l-Tetramisole Hydrochloride Levamisole Hydrochloride LEVAMISOLE HYDROCHLORIDE l-Tetramisole hydrochloride Ascaridil Decaris Ergamisol Ergamisole ICI-59623 Immunol Ketrax R 12564 R-12564 RP-20605 Solaskil Tramisol Trimisol
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Levamisole Hydrochloride
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|
| Legacy Concept Name |
Levamisole
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|
| NCI_Drug_Dictionary_ID |
39058
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|
| NSC Number |
177023
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|
| PDQ_Closed_Trial_Search_ID |
39058
|
|
| PDQ_Open_Trial_Search_ID |
39058
|
|
| Preferred_Name |
Levamisole Hydrochloride
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|
| prefixIRI |
Thesaurus:C610
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0733383
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| subClassOf |
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