loading...| Preferred Name | Hexestrol | |
| Synonyms |
(+-)-Hexestrol Cycloestrol Erythrohexestrol (.+-.)-Hexestrol (R*,S*)-4,4'-(1,2-Diethyl-1,2-ethanediyl)bis[phenol] HEXESTROL Hexestrol Sinestrol |
|
| Definitions |
A synthetic hydrogenated derivative of diethylstilbestrol (DES). Hexestrol exhibits strong affinity for estrogen receptors that are overexpressed in some types of cancers. When conjugated with a neoplastic drug, hexestrol may selectively concentrate the cytotoxic agent in estrogen receptor-rich tumors. This agent may also be mutagenic. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C545 |
|
| CAS_Registry |
5635-50-7 84-16-2 |
|
| Chemical_Formula |
C18H22O2 |
|
| code |
C545 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic hydrogenated derivative of diethylstilbestrol (DES). Hexestrol exhibits strong affinity for estrogen receptors that are overexpressed in some types of cancers. When conjugated with a neoplastic drug, hexestrol may selectively concentrate the cytotoxic agent in estrogen receptor-rich tumors. This agent may also be mutagenic. (NCI04) |
|
| FDA_UNII_Code |
10BI795R7D |
|
| FULL_SYN |
(+-)-Hexestrol Cycloestrol Erythrohexestrol (.+-.)-Hexestrol (R*,S*)-4,4'-(1,2-Diethyl-1,2-ethanediyl)bis[phenol] HEXESTROL Hexestrol Sinestrol |
|
| label |
Hexestrol |
|
| Legacy Concept Name |
Hexestrol |
|
| NSC Number |
9894 |
|
| Preferred_Name |
Hexestrol |
|
| prefixIRI |
Thesaurus:C545 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0019467 |
|
| subClassOf |