National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Antiestrogen
Synonyms

Estrogen Inhibitor

Antiestrogen Therapy

Antiestrogenic

Estrogen Antagonist

Anti-Estrogens

estrogen blocker

Antiestrogen

Antiestrogens

Antiestrogen Therapy Agent

antiestrogen

Definitions

Substances that inhibit or antagonize the biosynthesis or biologic effects of estrogens by either antagonizing the responsiveness of estrogen sensitive tissues or competing with their binding sites.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C481

ALT_DEFINITION

A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and pregnancy). Estrogen blockers may stop some cancer cells from growing and are used to prevent and treat breast cancer. They are also being studied in the treatment of other types of cancer. An estrogen blocker is a type of hormone antagonist.

CHEBI_ID

CHEBI:50837

CHEBI:50751

code

C481

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Substances that inhibit or antagonize the biosynthesis or biologic effects of estrogens by either antagonizing the responsiveness of estrogen sensitive tissues or competing with their binding sites.

Display_Name

Antiestrogen

FULL_SYN

Estrogen Inhibitor

Antiestrogen Therapy

Antiestrogenic

Estrogen Antagonist

Anti-Estrogens

estrogen blocker

Antiestrogen

Antiestrogens

Antiestrogen Therapy Agent

antiestrogen

label

Antiestrogen

Legacy Concept Name

Antiestrogen

Preferred_Name

Antiestrogen

prefixIRI

Thesaurus:C481

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0014930

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129818

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C547

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