loading...| Preferred Name |
Triamcinolone Hexacetonide |
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| Synonyms |
Triamcinolone Hexacetonide TRIAMCINOLONE HEXACETONIDE (11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione Aristospan |
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| Definitions |
The hexacetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone hexacetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48026 |
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| CAS_Registry |
5611-51-8 |
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| Chemical_Formula |
C30H41FO7 |
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| code |
C48026 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 |
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| Contributing_Source |
FDA GDC |
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| DEFINITION |
The hexacetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone hexacetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
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| FDA_UNII_Code |
I7GT1U99Y9 |
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| FULL_SYN |
Triamcinolone Hexacetonide TRIAMCINOLONE HEXACETONIDE (11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione Aristospan |
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| Is_Value_For_GDC_Property | ||
| label |
Triamcinolone Hexacetonide |
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| Legacy Concept Name |
Triamcinolone_Hexacetonide |
|
| Maps_To |
Triamcinolone Hexacetonide |
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| Preferred_Name |
Triamcinolone Hexacetonide |
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| prefixIRI |
Thesaurus:C48026 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0077004 |
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| subClassOf |