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National Cancer Institute Thesaurus
| Preferred Name | Oxycodone Hydrochloride | |
| Synonyms |
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride OXYCODONE HYDROCHLORIDE oxycodone hydrochloride Oxycodone Hydrochloride Oxecta OxyContin Roxicodone |
|
| Definitions |
The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48010 |
|
| Accepted_Therapeutic_Use_For |
Pain
|
|
| ALT_DEFINITION |
A drug used to treat moderate to severe pain. It is made from morphine and binds to opioid receptors in the central nervous system. Oxycodone hydrochloride is a type of analgesic agent and a type of opiate.
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|
| CAS_Registry |
124-90-3
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|
| CHEBI_ID |
CHEBI:7859
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|
| Chemical_Formula |
C18H21NO4.HCl
|
|
| code |
C48010
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism.
|
|
| Display_Name |
Oxycodone Hydrochloride
|
|
| FDA_UNII_Code |
C1ENJ2TE6C
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|
| FULL_SYN |
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride OXYCODONE HYDROCHLORIDE oxycodone hydrochloride Oxycodone Hydrochloride Oxecta OxyContin Roxicodone
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Oxycodone Hydrochloride
|
|
| Legacy Concept Name |
Oxycodone_Hydrochloride
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|
| NCI_Drug_Dictionary_ID |
508980
|
|
| PDQ_Closed_Trial_Search_ID |
508980
|
|
| PDQ_Open_Trial_Search_ID |
508980
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|
| Preferred_Name |
Oxycodone Hydrochloride
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|
| prefixIRI |
Thesaurus:C48010
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|
| Semantic_Type |
Pharmacologic Substance
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|
| UMLS_CUI |
C0722364
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| subClassOf |
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