Link to this page
National Cancer Institute Thesaurus
| Preferred Name | Fentanyl Citrate | |
| Synonyms |
FENTANYL CITRATE fentanyl citrate Fentanyl Citrate Actiq Fentanyl Fentyl Oralet Sublimaze |
|
| Definitions |
The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47994 |
|
| Accepted_Therapeutic_Use_For |
breakthrough pain in cancer patients.
|
|
| ALT_DEFINITION |
A drug used to treat severe cancer pain in that occurs even though the patient is already taking opioids. It is also used during anesthesia for surgery. Fentanyl citrate binds to opioid receptors in the central nervous system. It is a type of analgesic agent and a type of opioid.
|
|
| CAS_Registry |
990-73-8
|
|
| CHEBI_ID |
CHEBI:31602
|
|
| Chemical_Formula |
C22H28N2O.C6H8O7
|
|
| code |
C47994
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CPTAC CTRP FDA
|
|
| DEFINITION |
The citrate salt of fentanyl, a synthetic opioid related to the phenylpiperidines with analgesic and anesthetic properties. Fentanyl exerts its analgesic effect by selectively binding to the mu-opioid receptor in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. Additional pharmacological effects of fentanyl include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, and cough suppression.
|
|
| Display_Name |
Fentanyl Citrate
|
|
| FDA_UNII_Code |
MUN5LYG46H
|
|
| FULL_SYN |
FENTANYL CITRATE fentanyl citrate Fentanyl Citrate Actiq Fentanyl Fentyl Oralet Sublimaze
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Fentanyl Citrate
|
|
| Legacy Concept Name |
Fentanyl_Citrate
|
|
| NCI_Drug_Dictionary_ID |
39241
|
|
| PDQ_Closed_Trial_Search_ID |
39241
|
|
| PDQ_Open_Trial_Search_ID |
39241
|
|
| Preferred_Name |
Fentanyl Citrate
|
|
| prefixIRI |
Thesaurus:C47994
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0546864
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |