National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Betamethasone Dipropionate
Synonyms

BETAMETHASONE DIPROPIONATE

Betamethasone Dipropionate

Diprolene

Definitions

The 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47963

CAS_Registry

5593-20-4

CHEBI_ID

CHEBI:31276

Chemical_Formula

C28H37FO7

code

C47963

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

FDA_UNII_Code

826Y60901U

FULL_SYN

BETAMETHASONE DIPROPIONATE

Betamethasone Dipropionate

Diprolene

label

Betamethasone Dipropionate

Legacy Concept Name

Betamethasone_Dipropionate

Preferred_Name

Betamethasone Dipropionate

prefixIRI

Thesaurus:C47963

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0053523

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

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