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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ropinirole Hydrochloride | |
| Synonyms |
ROPINIROLE HYDROCHLORIDE 2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, Monohydrochloride 4-(2-(Dipropylamino)ethyl)-2-indolinone Monohydrochloride SK&F 101468-A Ropinirole Hydrochloride Requip |
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| Definitions |
The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47710 |
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| CAS_Registry |
91374-20-8
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|
| Chemical_Formula |
C16H24N2O.HCl
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|
| code |
C47710
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function.
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| FDA_UNII_Code |
D7ZD41RZI9
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| FULL_SYN |
ROPINIROLE HYDROCHLORIDE 2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, Monohydrochloride 4-(2-(Dipropylamino)ethyl)-2-indolinone Monohydrochloride SK&F 101468-A Ropinirole Hydrochloride Requip
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Ropinirole Hydrochloride
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|
| Legacy Concept Name |
Ropinirole_Hydrochloride
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|
| NCI_Drug_Dictionary_ID |
779013
|
|
| PDQ_Closed_Trial_Search_ID |
779013
|
|
| PDQ_Open_Trial_Search_ID |
779013
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|
| Preferred_Name |
Ropinirole Hydrochloride
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|
| prefixIRI |
Thesaurus:C47710
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|
| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0771840
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| subClassOf |
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