National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Rocuronium Bromide
Synonyms

Pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, Bromide

ROCURONIUM BROMIDE

Rocuronium Bromide

ORG 9426

Zemuron

Definitions

The bromide salt form of rocuronium, an intermediate-acting quaternary aminosteroid with muscle relaxant property. Rocuronium bromide competitively binds to the nicotinic receptor at the motor end plate, and antagonizes acetylcholine binding, which results in skeletal muscle relaxation and paralysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47709

CAS_Registry

119302-91-9

CHEBI_ID

CHEBI:8885

Chemical_Formula

C32H53N2O4.Br

code

C47709

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

The bromide salt form of rocuronium, an intermediate-acting quaternary aminosteroid with muscle relaxant property. Rocuronium bromide competitively binds to the nicotinic receptor at the motor end plate, and antagonizes acetylcholine binding, which results in skeletal muscle relaxation and paralysis.

Display_Name

Rocuronium Bromide

FDA_UNII_Code

I65MW4OFHZ

FULL_SYN

Pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, Bromide

ROCURONIUM BROMIDE

Rocuronium Bromide

ORG 9426

Zemuron

label

Rocuronium Bromide

Legacy Concept Name

Rocuronium_Bromide

NCI_Drug_Dictionary_ID

767623

PDQ_Closed_Trial_Search_ID

767623

PDQ_Open_Trial_Search_ID

767623

Preferred_Name

Rocuronium Bromide

prefixIRI

Thesaurus:C47709

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0591463

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29696

Delete Subject Author Type Created
No notes to display